Intestinal Transplantation
In Safe Hands
NASIT Forum meeting
Dates & locations
Monday 13 May 2013. 2pm
Addenbroke's Hospital
Cambridge University Hospital
NHS Trust,
Cambridge
26 - 29 June 2013
Oxford Town Hall
St. Aldate's
United Kingdom
http://www.isbts2013.org
Wednesday 10 July 2013. 2pm
John Radcliffe Hospital
Oxford
Monday 9 Sept 2013. 2pm
The Hope
Salford Royal Hospital
NHS Trust, Manchester.
Friday 22 Nov 2013. 2pm
St. Mark's Hospital,
Seminar room 5, Level 6
Unit
Watford Road Harrow
...
Monday 6 Jan 2014. 2pm
Addenbroke's Hospital
Cambridge University Hospital
NHS Trust,
Cambridge
Wednesday 5 Mar 2014
John Radcliffe Hospital
Oxford
Call:
History of Adult Intestinal Transplantation in the UK
The first intestinal transplantation undertaken in the UK was performed at Addenbrooke's hospital in Cambridge in 1991, under the leadership of Professor Sir Roy Calne. Since this time Addenbrooke's has provided the main adult service for the UK and is now has Mr Neville Jamieson as lead surgeon and Dr Stephen Middleton as lead physician. In addition to isolated intestinal transplants Addenbrooke's is commissioned by the National commissioning group (NCG) to transplant the liver and additional organs at the same time as the intestine should the need arise. Quite often, patients need more than just the intestine so this is a useful option. St Jame's hospital in Leed's also undertook several intestinal transplants in the mid 1990's under the leadership of Mr Steve Pollard. Oxford have recently been commissioned to undertake isolated intestinal transplants and undertook their first procedure in 2008, Professor Peter Friend heads the service. The results of intestinal transplantation have greatly improved over the last 15 years. The main area of improvement has been the first 2 years after the transplantation. This seems to be largely due to the use of better anti-rejection drugs. Some of these are given to reduce the number of white blood cells (lymphoctes) in the patient so that rejection is less of a problem. Addenbrooke's was one of the first centres to use this group of drugs called monoclonal antibodies, which have become the standard anti-rejection treatment for intestinal transplantation world wide. This is quite appropriate as this type of drug was first developed in Cambridge University, UK.
The two intestinal transplantation centres work closely with the two designated national centres for intestinal failure at St Mark's hospital, an academic centre in London (headed by Dr Simon Gabe), and The Hope hospital in Salford Manchester (headed by Dr Jon Shaffer). Most of the patients who require intestinal transplantation will have an initial assessment in one of these centres. There are also several other excellent smaller intestinal failure centres throughout the country who will from time to time refer their patients for consideration of transplantation.
With the increase in demand it was decided to initiate a single national forum where all those involved in undertaking these procedures could meet and discuss each potential candidate. This provides the essential ingredient of combined experience and expertise. This was founded between Addenbrooke's hospital Cambridge and St Mark's hospital London by Drs Stephen Middleton and Simon Gabe respectively and meets quarterly and has broad representation from all centres. It has now been designated as the listing meeting where patients need to be presented, discussed and subsequently approved before transplantation.